Spatial transcriptomics, or spatially resolved transcriptomics, is a method that captures positional context of transcriptional activity within intact tissue. [1]

This technology offers a novel perspective for understanding the spatial variations and distributions of gene expression. With the emergence of spatial transcriptomics, our ability to understand drug …

Jan 6, 2021 · Nature Methods has crowned spatially resolved transcriptomics Method of the Year 2020.

Jun 1, 2024 · Spatial transcriptomics has rapidly evolved from its conceptual beginnings into a powerful tool that offers unprecedented insights into the spatial distribution of gene expression within complex …

Jun 27, 2022 · Since spatial information is preserved by studying intact tissue, these methods have been referred to as spatially-resolved transcriptomics, or simply ‘spatial transcriptomics’.

Jul 30, 2025 · Spatial transcriptomics works by capturing RNA molecules from a tissue section and assigning them precise spatial coordinates. This creates a detailed map of gene expression across …

What is spatial transcriptomics? The goal of spatial transcriptomics is to measure gene expression (i.e. quantify mRNA transcripts) in the spatial context of a tissue sample. Genes, cells, and cell …

Spatial transcriptomic technology is used to parse RNA-seq data at the spatial level, which can simultaneously obtain the spatial context and transcriptional pattern of cells to improve our …

Apr 3, 2025 · Spatial transcriptomics enables gene expression mapping within tissues but is often limited by imaging constraints. We present an imaging-free approach that reconstructs spatial barcode...

Jun 26, 2025 · Spatial transcriptomics (ST) technologies have significantly advanced our capacity to quantify gene expression within tissue sections while preserving crucial spatial context information. …