New England Biolabs (NEB ®) today announced the launch of the NEBNext Enzymatic 5hmC-seq Kit (E5hmC-seq ™), a novel enzyme-based method for the specific detection of 5hmC sites. The gentle, ...

Existing genome-wide methylation technologies provide coarse-grained resolution. Pellegrini wanted single-base data on a genome-wide scale. Pellegrini and his colleagues combined bisulfite conversion ...

Structural variations (SVs)—large-scale changes in DNA sequence—play a crucial role in shaping traits such as yield, quality, and environmental adaptation in crops.

Chemical modifications to DNA and RNA play critical roles in gene regulation, development, viral infection, and human disease, including cancer and neurological disorders. More than 150 epigenetic and ...

Since the completion of the human genome project in 2003, structural and genetic factors within the genome are continuously being mapped to various diseases previously not considered to have genetic ...