Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to angiotensin-converting enzyme 2 (ACE2) sites on epithelial cells. This is mediated by the spike protein, which ...
Beijing Zhongke Journal Publising Co. Ltd. In summary, this work provides aninnovative strategy to ease CRISPR mutant identification and Cas9 transgene elimination using a single selection marker, ...
Genetic variants underlying life-threatening diseases, being unlikely to be transmitted to the next generation, are gradually and selectively eliminated from the population through negative selection.