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Every cell in the human body is surrounded by a semi-permeable membrane that needs to protect the contents of the cell while also allowing essential nutrients and ions to pass through. Compounds ...

Cell membranes cradle, protect, and gatekeep living cells. Membranes can even affect how a cell behaves. But membranes' own erratic behavior has puzzled scientists for years. Turns out, it's all about ...

When it comes to managing cholesterol in your body, your liver is key. Your liver makes cholesterol and sends it to other parts of your body where you need it. Your liver makes lipoproteins that carry ...

If your blood contains too much of the waxy substance called cholesterol, your risk of a heart attack or stroke from a clogged artery goes up. You may have inherited your high cholesterol, but diet ...

From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

The International Classification of Diseases, or ICD, is a classification system for all physical and mental diseases produced by the World Health Organization (WHO). It’s used for diagnosis, research ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

PR1, W1, T51, F58, SL4, KL3, SM11. This is not a test to crack a code. But you will see a series of letter and number combinations while engaging with the Paralympics in Paris. At the Olympics, there ...