Network control theory can describe the photochemical isomerization of glucose to allose. This transformation, in which the hydroxy group on a single carbon flips from one stereochemical configuration ...

ABSTRACT: D-allulose, also known by the name D-psicose or just allulose, is a rare keto-sugar epimer of D-fructose in the third carbon (C3), and naturally occurs in small quantity in fruits such as ...

Thalidomide, one of the most infamous drugs of all, caused severe birth defects in the children of pregnant women who took the drug for nausea in the 1950s. Its story has been repeated over and over – ...

Chemists report a concise synthesis of pleurotin by way of the Diels-Alder reaction and a radical epimerization. Their late-stage intermediate intersects a milestone 1988 synthesis, reducing the total ...

An 8-step synthesis of a known pentacyclic intermediate toward the natural product pleurotin (1) is described. Pleurotin and related benzoquinone natural products are of great interest for their ...

To face the current antibiotic resistance crisis, novel strategies are urgently required. Indeed, in the last 30 years, despite considerable efforts involving notably high-throughput screening and ...

Azlactones are versatile heterocycles employed in a diversity of transformations; the main drawback of these cycles consists in the epimerization of the α-carbonyl stereocenter during its preparation.

1 Tea Research Institute, Fujian Academy of Agricultural Sciences, Fu’an, China 2 Key Laboratory of Tea Plant Biology and Resources Utilization, Ministry of Agriculture, National Center for Tea ...

Inorganic catalysts can provide alternative chemical pathways to those offered by biological systems. In contrast to enzymes, inorganic catalysts function over a larger range of reactant purities, ...