As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...

Research shows hair follicle aging begins in your 30s, driven by inflammation-linked gene activity detectable years before ...

Hair loss and graying, the earliest visible signs of skin aging, are fundamentally driven by the functional decline of the hair follicle stem cells ...

Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem ...

Mechano-Growth Factor (MGF), often referred to as the IGF-1 Ec isoform (or IGF-1 Eb), is a splice variant of the insulin-like ...

The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...

This important study provides a detailed analysis of the transcriptional landscape of the mouse hippocampus in the context of various physiological states. The main conclusions have solid support: ...

Study at the University of Colorado Anschutz Cancer Center builds on preclinical data showing that cirtuvivint plus PARP inhibition overcame resistance in preclinical models of high‑grade serous ovari ...

This is a solid paper on intermittent fasting that will be of interest to readers. The data presented are certainly valuable as a resource. The findings of both shared and tissue-specific signatures, ...

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the head group of phosphoinositide lipids in the cytoplasmic leaflet of subcellular membranes and thereby regulate signaling and membrane dynamics. The ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In early-stage estrogen receptor-positive (ER ...