Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.

Slide viewers have evolved dramatically from the bulky, temperamental machines many of us remember. The days of wrestling a heavy projector out of storage just to check a few frames are long gone.

Fresh, cultured control and treated cultured ovarian fragments were fixed in buffered 4% paraformaldehyde in phosphate buffered saline (PBS) for 12 h at 4°C, dehydrated in a graded series of ethanol, ...