For a monovalent species, a simple calculation that does not assume partitioning of the ionized species in the oil phase can provide an accurate estimate of the distribution coefficient. Get the ...
Objectives The partitioning of lipophilic toxicants into blood and into adipose tissue plays an important role in the physiological distribution and toxicology of these substances. The partition ...
Figure 1: Standard curves used to determine a suitable drug concentration for the assay. Figure 2: Representation of the 96-well microplate used in this protocol. This material is hazardous when in ...