In spite of its stereotypic laminar and columnar organization, the cerebral neocortex displays numerous species-specific adaptations of old and acquired new traits that subserve specific functions ...

Attempts to understand brain function benefit from both experimental and computational approaches. Markram et al. report on the progress of the Blue Brain Project, a European initiative that has ...

This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.