New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...
New research in The American Journal of Pathology has identified neuroinflammation, driven by microglia (immune cells), as a ...
Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage.
“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who ...
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...
In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary immune ...
Ever since loss-of-function variants in the gene for PILRA, short for paired immunoglobulin-like type 2 receptor alpha, turned up as protecting against Alzheimer’s disease, scientists have wondered ...