Alzheimer’s disease has long looked like a slow-motion wildfire, starting in one part of the brain and then advancing along ...

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage.

“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...

In Alzheimer’s disease, microglia act as a double-edged sword. They can either protect the brain or worsen the damage, depending on their activation state. Inflammatory activation harms healthy ...

Immune-regulating brain cells known as microglia are known to play a role in the progression of Alzheimer’s disease (AD). Investigators at Brigham and Women’s Hospital studying the genetics of ...

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord ...

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development. By incorporating ...

Ever since loss-of-function variants in the gene for PILRA, short for paired immunoglobulin-like type 2 receptor alpha, turned up as protecting against Alzheimer’s disease, scientists have wondered ...

More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...