Network control theory can describe the photochemical isomerization of glucose to allose. This transformation, in which the hydroxy group on a single carbon flips from one stereochemical configuration ...

Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E, P.O. Box 56, 00014 Helsinki, Finland School of Chemistry and ...

ABSTRACT: D-allulose, also known by the name D-psicose or just allulose, is a rare keto-sugar epimer of D-fructose in the third carbon (C3), and naturally occurs in small quantity in fruits such as ...

Thalidomide, one of the most infamous drugs of all, caused severe birth defects in the children of pregnant women who took the drug for nausea in the 1950s. Its story has been repeated over and over – ...

Chemists report a concise synthesis of pleurotin by way of the Diels-Alder reaction and a radical epimerization. Their late-stage intermediate intersects a milestone 1988 synthesis, reducing the total ...

To face the current antibiotic resistance crisis, novel strategies are urgently required. Indeed, in the last 30 years, despite considerable efforts involving notably high-throughput screening and ...

Azlactones are versatile heterocycles employed in a diversity of transformations; the main drawback of these cycles consists in the epimerization of the α-carbonyl stereocenter during its preparation.

Deoxynivalenol (DON, also known as vomitoxin) is a toxic secondary metabolite produced by several Fusarium species including Fusarium graminearum and F. culmorum (Audenaert et al., 2014). It is one of ...

Tyrocidine, a macrocyclic decapeptide from Bacillus brevis, is nonribosomally assembled by a set of multimodular peptide synthetases, which condense two D-amino acids and eight L-amino acids to ...

Inorganic catalysts can provide alternative chemical pathways to those offered by biological systems. In contrast to enzymes, inorganic catalysts function over a larger range of reactant purities, ...