Abstract: This paper defines a new combinatorial optimization problem, namely General Combinatorial Optimization Problem (GCOP), whose decision variables are a set of parametric algorithmic components ...

Abstract: Combinatorial problems are formulated to find optimal designs within a fixed set of constraints and are commonly found across diverse engineering and scientific domains. Understanding how to ...

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Combinatorial chemistry has been widely adopted by the pharmaceutical industry in the past decade. However, owing to perceived “failures” with this technology, the pharmaceutical industry has been ...