Mapping gene disruptions in sporadic early onset Alzheimer's disease across key brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

Schizophrenia: The cerebellum's unexpected role

Apathy, social withdrawal, and loss of motivation—the so-called ''negative'' symptoms of schizophrenia—are among the most ...

Brain neurons process salience, valence and value separately to understand what is important—and what isn't

The sound of a fire alarm tells us to get out quickly to not get hurt, while the sight of a gas station sign can signal a ...
News-Medical.Net

Researchers uncover unexpected role of the cerebellum in schizophrenia's negative symptoms

Apathy, social withdrawal, and loss of motivation — the so-called ''negative'' symptoms of schizophrenia — are among the most ...
eLife

Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

The orbitofrontal cortex (OFC) is critical to identifying task structure and to generalizing appropriately across task states with similar underlying or hidden causes. This capability is at the heart ...

Spaceflight causes astronauts' brains to shift, stretch and compress in microgravity

Spaceflight takes a physical toll on astronauts, causing muscles to atrophy, bones to thin and bodily fluids to shift.