Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Membrane proteins are key targets for therapeutic intervention using antibody biologics. Over 60% of FDA-approved drugs act on these proteins. Studying them is challenging because the proteins must be ...

The targeted treatment of brain diseases such as Alzheimer’s, Parkinson’s or brain tumours is challenging because the brain is a particularly sensitive organ that is well protected. That’s why ...

A new paper by a team of Concordia researchers from the departments of Biology and Physics proposes a novel method of fighting cancer tumors that uses ultrasound-guided microbubbles - a technology ...

Beta-coronaviruses, including SARS-CoV-2, have caused global health problems. How the virus infects host cells and triggers immunological responses has been investigated extensively. However, how the ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...

Dynamin is a protein that plays a central role in endocytosis—the process where cells internalize substances by wrapping them in cell membrane vesicles. For a vesicle to detach, the neck of the ...

Researchers at ETH Zurich have developed artificial muscles that contain microbubbles and can be controlled with ultrasound. In the future, these muscles could be deployed in technical and medical ...