CHANGES of volume accompanying enzyme hydrolysis have been utilised by Sreenivasaya and Sastry 1 to follow the kinetics of enzyme action by means of the dilatometer. The procedure employed in the ...

Researchers defined the structure of a substrate-bound iron 2-oxoglutarate (Fe/2OG) enzyme to explore whether these enzymes could be used to create a wide array of molecules. They saw that Fe/2OG ...

A research team maps the key tasks that define modern enzyme engineering—function annotation, structure modeling, and property prediction—and explain how AI methods now accelerate each step, from ...

Real-time measurement of the initial stage of an enzyme–substrate reaction is essential for reproducible enzyme kinetics data. Automated direct-flow injection systems couple with various detection and ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

Reactions that can combine more than two molecular pieces in one go are a powerful way to build complexity quickly and save on costly isolation and purification. But the choreography for such a ...

Chemical engineers have developed an online tool that can accurately assign genes and proteins to unknown 'orphan' reactions, which are a major headache for biotechnology, drug development, and even ...

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...

A team of agricultural and environmental scientists has developed a simple biochar based technology that can strip self toxic ...

Analysts interested in small volume sample preparation, culture growth, enzyme preservation, enzyme-substrate reactions, DNA amplification, electrophoresis gel degeneration, or serum coagulation ...