Checkpoint inhibitors are antibody-based cancer therapies that unlock the immune system’s natural ability to fight cancer. These treatments work by blocking special proteins called immune checkpoints, ...

3D rendering of a checkpoint inhibitor binding PD-1, a protein on the surface of an immune T cell. This article is part of an ongoing series on checkpoint inhibitors, a novel cancer immunotherapy.

Humans have been attempting to combat cancer since the time of the Ancient Egyptians, and recent decades have seen remarkable progress. However, tumor cells have developed sophisticated ways to evade ...

In a recent study published in Cell, a group of researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of progestogen-induced B7 Homolog 4 (B7-H4) ...

Have you ever toiled for hours on a document only to have your computer crash just as the last line gets written? From that type of experience, most users learn to save early and often so their work ...