The Min protein system prevents abnormal cell division in bacteria, but is poorly understood. Researchers have uncovered how engineered e.coli bacteria control protein levels for maximum efficiency.

Researchers have found a molecular mechanism that prevents multiplication of potentially dangerous cells by measuring the duration of mitosis. They have shown that this mechanism -- the Mitotic ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...

The Min protein system prevents abnormal cell division in bacteria by forming oscillating patterns between the ends of a cell ("poles"). Despite decades of theoretical work, predicting the protein ...

Chimeric antigen receptor-T cell (CAR-T cell) therapies have been a significant advance in the field of cancer immunotherapeutics in recent years, particularly for B-cell malignancies. Yet, this ...

Longitudinal sections of inflorescence stems of wild type (WT) (left) and at2-mmp mutant (right) at 7 days after incision. Arrowheads indicate the position of incision. Scale bars, 100 μm. Overall, ...

Cells can measure how long they spend in mitosis. If mitosis is prolonged due to problems during chromosome separation, the Mitotic Stopwatch Complex is formed, which may lead to cell arrest or cell ...